Antimicrobial Properties of Combined Acalypha Extracts: Addressing Drug Resistance in Microbes

Abstract

The increasing resistance of microbes to conventional chemotherapeutic agents necessitates the exploration of new antimicrobial agents. This study investigates the antimicrobial potential of combined methanolic extracts of Acalypha hispida, Acalypha nervosa, and Acalypha fruticosa. These plants, known for their medicinal properties, were tested against selected microbial strains to evaluate their efficacy. The combined extracts exhibited significant antimicrobial activity, showing potent inhibitory effects on both bacterial and fungal pathogens. The results indicate that the synergistic effect of the three Acalypha species enhances their antimicrobial properties, making them a promising source of natural compounds for the development of new antimicrobial agents. These findings suggest the potential of using Acalypha species in combating microbial infections, particularly in light of growing resistance to synthetic drugs. Further studies are recommended to isolate and identify the active compounds responsible for the observed activity and to evaluate their safety and effectiveness in clinical settings.